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RMI Equation:
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The Risk of Malignancy Index (RMI) is a scoring system used to estimate the risk of ovarian cancer in women with pelvic masses. It combines ultrasound findings, menopausal status, and CA125 levels to provide a quantitative assessment of malignancy risk.
The calculator uses the RMI equation:
Where:
Explanation: The RMI combines multiple clinical parameters to provide a more accurate assessment of ovarian cancer risk than any single parameter alone.
Details: The RMI helps clinicians stratify patients with pelvic masses into low, intermediate, and high-risk categories, guiding appropriate management decisions including referral to specialized centers.
Tips: Enter the ultrasound score (typically 0-3), menopausal status score (1 for premenopausal, 3 for postmenopausal), and CA125 level in U/mL. All values must be positive numbers.
Q1: What are typical ultrasound scoring criteria?
A: Ultrasound features may include multilocular cysts, solid areas, bilateral lesions, ascites, and intra-abdominal metastases. Each feature typically contributes 1 point to the U score.
Q2: How is menopausal status determined?
A: Postmenopausal is defined as more than 1 year of amenorrhea or age over 50 with previous hysterectomy. Premenopausal women receive a score of 1, postmenopausal women receive a score of 3.
Q3: What are the RMI risk categories?
A: Typically, RMI < 25 indicates low risk, 25-250 indicates intermediate risk, and >250 indicates high risk of malignancy.
Q4: What are the limitations of RMI?
A: RMI may be less accurate in premenopausal women, women with borderline tumors, or those with non-ovarian cancers that elevate CA125.
Q5: Should RMI replace clinical judgment?
A: No, RMI is a tool to assist clinical decision-making but should not replace comprehensive clinical assessment and specialist consultation.