1. What is the Risk of Malignancy Index?

The Risk of Malignancy Index (RMI) is a scoring system used to estimate the risk of ovarian malignancy in pregnancy. It combines ultrasound findings, menopausal status, and CA125 levels to provide a quantitative assessment.

2. How Does the Calculator Work?

The calculator uses the RMI formula:

Where:

• \( U \) — Ultrasound score (unitless)
• \( M \) — Menopausal status score (unitless)
• \( CA125 \) — CA125 level (U/mL)

Explanation: The RMI multiplies the ultrasound score, menopausal status score, and CA125 value to generate a malignancy risk index.

3. Importance of RMI Calculation

Details: RMI calculation helps clinicians assess the risk of ovarian malignancy during pregnancy, guiding further diagnostic evaluation and management decisions.

4. Using the Calculator

Tips: Enter ultrasound score, menopausal status score, and CA125 level. All values must be valid non-negative numbers.

5. Frequently Asked Questions (FAQ)

Q1: What are typical ultrasound score values?
A: Ultrasound scores typically range from 0-3 based on specific morphological features of ovarian masses.

Q2: How is menopausal status scored?
A: Premenopausal status is usually scored as 1, while postmenopausal status is scored as 3 in most RMI systems.

Q3: What CA125 levels are concerning?
A: CA125 levels above 35 U/mL are generally considered elevated, but interpretation depends on clinical context.

Q4: What RMI values indicate high risk?
A: RMI values above 200 are generally considered high risk for ovarian malignancy.

Q5: Are there limitations to RMI in pregnancy?
A: CA125 levels can be elevated in normal pregnancy, so RMI interpretation requires careful clinical correlation.