Sle Das Calculator

DAS28 Equation:

\[ DAS28 = 0.56 \times \sqrt{tender\ joints} + 0.28 \times \sqrt{swollen\ joints} + 0.70 \times \ln(ESR) + 0.014 \times VAS \]

Tender Joints (count):

count

Swollen Joints (count):

count

ESR:

mm/hr

VAS:

0-100

DAS28 Score:

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1. What is the DAS28 Equation?

The DAS28 (Disease Activity Score for 28 joints) is a measure of disease activity in rheumatoid arthritis and systemic lupus erythematosus. It assesses tender and swollen joint counts, erythrocyte sedimentation rate (ESR), and patient's global assessment of disease activity.

2. How Does the Calculator Work?

The calculator uses the DAS28 equation:

\[ DAS28 = 0.56 \times \sqrt{tender\ joints} + 0.28 \times \sqrt{swollen\ joints} + 0.70 \times \ln(ESR) + 0.014 \times VAS \]

Where:

\( tender\ joints \) — Number of tender joints (count)
\( swollen\ joints \) — Number of swollen joints (count)
\( ESR \) — Erythrocyte sedimentation rate (mm/hr)
\( VAS \) — Visual analog scale (0-100)

Explanation: The equation combines objective measures of inflammation (joint counts, ESR) with subjective patient assessment (VAS) to provide a comprehensive disease activity score.

3. Importance of DAS28 Calculation

Details: DAS28 scoring is crucial for monitoring disease activity, guiding treatment decisions, and assessing treatment response in rheumatoid arthritis and systemic lupus erythematosus patients.

4. Using the Calculator

Tips: Enter tender joint count (0-28), swollen joint count (0-28), ESR value (must be >0), and VAS score (0-100). All values must be valid for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What do different DAS28 scores indicate?
A: DAS28 > 5.1 indicates high disease activity, 3.2-5.1 moderate activity, 2.6-3.2 low activity, and < 2.6 indicates remission.

Q2: Which 28 joints are assessed?
A: The 28 joints include shoulders, elbows, wrists, MCP joints, PIP joints, and knees (bilaterally).

Q3: How often should DAS28 be measured?
A: Typically every 3-6 months during active disease, or more frequently when adjusting treatment.

Q4: Are there limitations to DAS28?
A: DAS28 may not capture all aspects of disease, particularly extra-articular manifestations, and may be less sensitive in patients with longstanding disease.

Q5: Can DAS28 be used for treatment decisions?
A: Yes, DAS28 is widely used to guide treatment intensification or de-escalation in rheumatoid arthritis management.